Amerisleep has been around for over a decade, which is much longer than most other direct-to-consumer mattress companies around right now. The Amerisleep AS5 and AS5 Hybrid are their premium-level mattresses made for people who prefer a soft mattress, but want to avoid that "stuck" feeling you get with traditional memory foam.

Amerisleep built this mattress with their proprietary BioFoam, which is similar to memory foam, but is more responsive, cooler, and has anti-mold and mildew properties. It feels slightly like memory foam, but instead of feeling like you're being sucked into the mattress, you feel supported on pressure points. This soft, yet supportive feature also makes Amerisleep one of the best mattresses for stomach sleepers.

If you're in the market for a premium soft mattress that's built to last 20+ years, give this one a shot. If you don't like it, you have 100 days to send it back (free shipping both ways).

For comfort and shoulder support, and Layla Sleep has you covered. Four layers of foam provide cooper infused coolness and your choice of support. You even get to choose you level of support. This mattress is reversible. One side is mid-soft comfort and is great for those who want to sink into the bed a bit. Flip it over to the comfort layer for a firmer comfort. Both sides are copper infused to transfer heat rapidly and can help prevent shoulder pain. You get a 120-night trial, so you can test it out to see if it relieves any shoulder pain you may experience.

Shoulder pain arises most commonly in side sleepers, or those with pre-existing conditions that irritate their shoulder while they sleep. The Nolah Original 10" mattress is designed to help relieve pressure, especially for side sleepers. If you have shoulder pain, you need a mattress that has enough give to relieve the high pressure that tends to appear in that area. 

This all foam mattress offers next-level pressure relief, but also keeps you cool while you sleep, which is great if you tend to get hot during the night. This mattress also comes with a 100 night trial and a lifetime warranty which makes it a safe bet if you plan on purchasing a mattress online. Want to know more? Read the full Nolah mattress review.

Sweetnight wants to ensure that you have a sweet night with this 10-inch mattress. This mattress was created with back pain in mind, and it will definitely help with shoulder pain too. Cool gel works to regulate temperatures and provide extra support and alignment to your body.

As one of the best mattresses for back sleepers, this medium firm mattress will relieve pressure points from head to toe, allowing you to get the best night’s sleep. Meanwhile, the middle layers are designed for durability and proper airflow. You will get continuous support for long-term use without the sags and dips that happen quickly in other mattresses. Use code SLEEPSHOP at checkout to get the best discount available.

Tuft and Needles uses a high-grade foam that differs from the typical latex mattress or memory foam that we are used to seeing. Specially engineered to relieve pressure on your body and adapt to your shape, this mattress is great for any sleep position. Shoulder relief should come quickly. However, if you sleep on your side and you prefer a softer feel, consider buying the best mattresses for side sleepers. Luckily, this brand wants you to have time to adjust to your new bed and offers a 100-day trial period.

Crafted with gel and graphite to keep you cool, you won’t be up half the night trying to find a cool spot during hot summer months. If you have joint or shoulder pain that causes warmth, this mattress should not exacerbate that.

Nectar brand is quickly earning a name in e-commerce as a great bed-in-a-box producer. They back their brand and products up with an industry leading 180-night trial and a warranty that lasts for as long as you own the mattress. Your purchase will include two premium pillows, which is a great value. Those of us with shoulder problems know that the right pillow can also make a world of a difference as well.

Aches and pains will melt away as you lay on this cushiony, cool mattress. Each foam layer is crafted for a specific purpose and aids in your comfort. Its breakability help keep the temperature regulated.

Ashley Furniture brings us a budget friendly mattress that is not lacking in comfort. This is the best memory foam that contours to your body as you sleep keeps you cozy while encouraging deep sleep. Plush feel with support foam core that reduces motion and relieves pressure. Shoulder pain prevention and other pressure points will feel relief with this mattress.

Those with allergies or asthma that is affected by irritants like pollen, mold, and pet dander will love the hypoallergenic material. The material keeps out dust mites and other dirt and debris, so clean up and maintenance are easy.

If you're suffering from shoulder pain and looking for the best hybrid mattress for side sleepers, it's time to give the Classic Brands Cool Gel 2.0 a try. Classics Brands does not falter with this classic memory mattress. The mattress pad is a thick 14-inches, so each foam layer gets the perfect density to do its job right. Pressure relieving base foam provides support while keeping your shoulders and body aligned. Meanwhile, the poly foam gel layer is plush for extra comfort and a cozy night’s sleep.

You will receive 2 shredded memory foam pillows with your purchase. While the bed keeps your back, hips and shoulders in order, the pillow supports your head and neck. This support will prevent neck stress and pulling, which can cause more shoulder pain.